Congenital syphilis with nephrotic syndrome

A patient with congenital syphilis and nephrotic syndrome is reported. The renal biopsy with light microscope showed glomerulopathy with epithelial proliferation. Irregular, nodular, electrodense material was identified with the electron microscope in subepithelial spaces and immunofluorescence show...

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Bibliographic Details
Published in:	Boletín médico del Hospital Infantil de México (Spanish edition) Vol. 36; no. 3; p. 425
Main Authors:	Reynoso García, M, Vargas Rosendo, R
Format:	Journal Article
Language:	Spanish
Published:	Mexico 01-05-1979
Subjects:	Biopsy Diagnosis, Differential Gentamicins - therapeutic use Humans Infant, Newborn Kidney - pathology Male Nephrotic Syndrome - complications Nephrotic Syndrome - drug therapy Penicillins - therapeutic use Syphilis, Congenital - complications Syphilis, Congenital - drug therapy
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Summary:	A patient with congenital syphilis and nephrotic syndrome is reported. The renal biopsy with light microscope showed glomerulopathy with epithelial proliferation. Irregular, nodular, electrodense material was identified with the electron microscope in subepithelial spaces and immunofluorescence showed irregular granular positivity for IgG, IgM and fibrin, which confirmed a disease due to immune complexes. Pencillin and physical rehabilitation were sufficient therapy for the recovery of this patient.
ISSN:	0539-6115