EMILIN3, an extracellular matrix molecule with restricted distribution in skin

EMILIN3 is an extracellular matrix glycoprotein that displays a dynamic and restricted expression pattern in connective tissues during post‐natal life. In this study, we report the characterization of EMILIN3 deposition in the skin. In addition, to unravel the functions of this protein in skin homeo...

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Bibliographic Details
Published in:	Experimental dermatology Vol. 26; no. 5; pp. 435 - 438
Main Authors:	Corallo, Diana, Schiavinato, Alvise, Bizzotto, Dario, Milanetto, Martina, Guljelmovic, Marija, Keene, Douglas R., Sengle, Gerhard, Braghetta, Paola, Bonaldo, Paolo, Rendl, Michael
Format:	Journal Article
Language:	English
Published:	Denmark Wiley Subscription Services, Inc 01-05-2017
Subjects:	Animals Connective tissues EMILIN Extracellular matrix Extracellular Matrix Proteins - metabolism Glycoproteins - metabolism Hair hair follicle Hair Follicle - growth & development Hair Follicle - metabolism Homeostasis Mice Rodents Skin hair follicle EMILIN extracellular matrix
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Summary:	EMILIN3 is an extracellular matrix glycoprotein that displays a dynamic and restricted expression pattern in connective tissues during post‐natal life. In this study, we report the characterization of EMILIN3 deposition in the skin. In addition, to unravel the functions of this protein in skin homeostasis, we generated Emilin3 null mice and provide evidence that EMILIN3 is dispensable for hair follicle growth and maintenance throughout adult life.
Bibliography:	SourceType-Other Sources-1 ObjectType-Article-2 content type line 63 ObjectType-Correspondence-1
ISSN:	0906-6705 1600-0625
DOI:	10.1111/exd.13254