Soft tissue tumors of the anorectum: rare, complex and misunderstood

• Published in: Journal of gastrointestinal oncology Vol. 4; no. 1; pp. 82 - 94
• Main Authors: Nassif, Mohammed O, Trabulsi, Nora H, Bullard Dunn, Kelli M, Nahal, Ayoub, Meguerditchian, Ari-Nareg
• Format: Journal Article
• Language: English
• Published: China Pioneer Bioscience Publishing Company 01-03-2013
• Subjects: Review; rectum; sarcoma; Soft tissue neoplasms; anus; surgery
• ISSN: 2078-6891; 2219-679X
• DOI: 10.3978/j.issn.2078-6891.2012.042

Anorectal soft tissue tumors are uncommon and often present both diagnostic and therapeutic challenges. Although many of these tumors are identified with imaging performed for unrelated reasons, most present with nonspecific symptoms that can lead to a delay in diagnosis. Historically, radical surgery (abdominoperineal resection) has been the mainstay of treatment for both benign and malignant anorectal soft tissue tumors. However, a lack of proven benefit in benign disease along with changes in technology has called this practice into question. In addition, the role of radiation and/or chemotherapy remains controversial. In this manuscript, we review the history and current status of anorectal soft tissue tumor management, with a particular focus on challenges in optimizing survival.