Disseminated Vitiligo Developing Around Kaposi Sarcoma Nodules in an AIDS Patient

• Published in: Cutis (New York, N.Y.) Vol. 88; no. 5; pp. 237 - 239
• Main Authors: ELSAIE, Mohamed L, MOHAMED SHEHU, Yusuf, SANI, Mahmoud U, BORODO, Musa M, MOHAMMED, Aminu Z
• Format: Journal Article
• Language: English
• Published: Plainview, NY Quadrant HealthCom 01-11-2011
• Subjects: Adult; Biological and medical sciences; Biopsy; Dermatology; Diagnosis, Differential; HIV Infections - complications; Human viral diseases; Humans; Infectious diseases; Male; Medical sciences; Pigmentary diseases of the skin; Sarcoma, Kaposi - diagnosis; Sarcoma, Kaposi - immunology; Sarcoma, Kaposi - virology; Tumors of the skin and soft tissue. Premalignant lesions; Viral diseases; Viral diseases of the lymphoid tissue and the blood. Aids; Vitiligo - diagnosis; Vitiligo - immunology; Vitiligo - virology; Human; Immunopathology; Skin disease; Pigmentation disorder; Dermatology; AIDS; Malignant tumor; Immune deficiency; Nodule; Infection; Kaposi sarcoma; Vitiligo; Viral disease; Disseminated; Cancer
• ISSN: 0011-4162; 2326-6929

Vitiligo and other autoimmune disorders are increasingly being reported in a background of immunosuppression. Viral-induced immune activation and molecular mimicry are the proposed mechanisms for the development of autoimmune diseases in individuals infected with human immunodeficiency virus (HIV). An association of vitiligo with Kaposi sarcoma (KS) rarely has been reported. The development of vitiligo preferentially around KS lesions in a patient with AIDS is unusual. We report a case of disseminated vitiligo that developed around KS nodules in a patient with AIDS.