Comparison of the Ratio of the Lenght of the Second and Fourth Digits in Subgroups of Fertile and Infertile Cases

• Published in: Urology journal Vol. 14; no. 3; pp. 3081 - 3084
• Main Authors: Akinsal, Emre Can, Demirtas, Abdullah, Ekmekcioglu, Oguz
• Format: Journal Article
• Language: English
• Published: Iran Urology and Nephrology Research Center 23-05-2017
• Subjects: Azoospermia - pathology; Fingers - anatomy & histology; Humans; Hypogonadism - pathology; Infertility; Infertility, Male - pathology; Klinefelter Syndrome - pathology; Male; Oligospermia - pathology; Prospective Studies; Sperm; Sperm Count; Vas Deferens - abnormalities
• ISSN: 1735-1308; 1735-546X

To identify any relationship between known reasons of male infertility and 2D:4D ratio.
A total of 371 males were included in the study. The cases were grouped into 6 groups including sperm count < 5 million/mL, sperm count ≥ 5 million/mL, Klinefelter Syndrome, hypogonadotropic hypogonadism, vasal agenesis and control. Groups were compared with each other in terms of 2D:4D ratios and groups with a 2D:4D ratios below 1 and equal/above 1 were compared.
The greatest ratios were in the vasal agenesis and hypogonadotropic hypogonadism groups and analysis of the data with logistic regression analysis showed that there was a significant difference in terms of 2D:4D ratios for these groups when comparing with control group. The other groups showed no statistically significantdifferences.
The results of the present study showed some significant difference between 2D:4D ratios for the subgroups of the fertile and infertile cases. Although, 2D:4D ratio is not an unaccompanied parameter to reveal causes of male infertility, it can be associated with some situations that are related with male infertility.