Expression of the Xenopus laevis metallothionein gene during ontogeny

Expression of the Xenopus laevis metallothionein gene during ontogeny

Expression of the Xenopus laevis metallothionein (MT) gene was studied by in situ hybridization throughout development. MT mRNA was detected from the tailbud stage onwards. MT expression was observed in bucco-pharyngeal epithelium, pronephros and liver anlagen, aswell as in lens and periventricular...

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Bibliographic Details
Published in:The International journal of developmental biology Vol. 43; no. 6; pp. 575 - 578
Main Authors: Durliat, M, Muller, J P, André, M, Wegnez, M
Format: Journal Article
Language:English
Published: Spain 01-09-1999
Subjects:
Animals
Embryo, Nonmammalian
Freshwater
In Situ Hybridization
Larva
Metallothionein - genetics
Metallothionein - metabolism
Morphogenesis
MT gene
Organ Specificity
Reverse Transcriptase Polymerase Chain Reaction
RNA, Messenger - analysis
Xenopus laevis
Zinc - metabolism
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Summary:Expression of the Xenopus laevis metallothionein (MT) gene was studied by in situ hybridization throughout development. MT mRNA was detected from the tailbud stage onwards. MT expression was observed in bucco-pharyngeal epithelium, pronephros and liver anlagen, aswell as in lens and periventricular areas of the encephalon. MT transcripts, in both larvae and adults, were detected in diverse regions of the central nervous system and in differentiating tissues implicated in detoxification processes: liver hepatocytes, small intestine epithelia and kidney tubules. These data are discussed in the context of MT functions and support a physiological role for MT in growth processes.
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ISSN:0214-6282