Intervertebral disc lesions in diffuse idiopathic skeletal hyperostosis (DISH)

• Published in: Clinical and experimental rheumatology Vol. 19; no. 3; pp. 310 - 312
• Main Authors: DI GIROLAMO, C, PAPPONE, N, RENGO, C, MINIERO, E, CRISCI, C, OLIVIERI, I
• Format: Journal Article
• Language: English
• Published: Pisa Clinical and Experimental Rheumatology 01-05-2001
• Subjects: Adult; Age Distribution; Aged; Biological and medical sciences; Diseases of the osteoarticular system; Diseases of the spine; Female; Humans; Hyperostosis, Diffuse Idiopathic Skeletal - epidemiology; Hyperostosis, Diffuse Idiopathic Skeletal - pathology; Intervertebral Disc - pathology; Male; Medical sciences; Middle Aged; Prevalence; Human; Radiodiagnosis; Spine; Diseases of the osteoarticular system; Spine disease; Radiography; Symptomatology; Ankylosing hyperostosis; Correlation analysis; Criterion; Arthropathy; Degenerative disease; Diagnosis; Osteoarthritis; Intervertebral disk
• ISSN: 0392-856X; 1593-098X

In order to evaluate the relationships between DISH and vertebral osteochondrosis (degenerative disc disease), the radiographs of the spine of 69 DISH patients were compared to those of 68 controls.
Radiographs of 69 patients affected by DISH according to Resnick's criteria and of 68 control subjects affected by diseases other than DISH, were evaluated in order to determine the prevalence of vertebral osteochondrosis, diagnosed by the occurrence of moderate to severe reduction in the intervertebral disc height and of the extensive radiographic changes typical of degenerative disc disease, including vacuum phenomena and vertebral body marginal sclerosis. The rate ratios with 95% confidence intervals were computed, with stratification by age groups.
Thirty-eight DISH patients (55.1%) and 34 controls (50%) showed vertebral osteochondrosis. Stratification by age revealed an increased prevalence of vertebral osteochondrosis in younger DISH patients with respect to controls (p < 0.05).
Our results show that vertebral osteochondrosis may be associated with DISH and underline the differences between classification and diagnostic criteria. Moreover, it could be hypothesized that DISH plays a predisposing role in the development of vertebral osteochondrosis during the early stages of the disease, causing an early modification in the physiological curves of the spine.