Hyperpigmentation, vitiligo, and Addison's disease

Addison's disease is an uncommon disorder whose dermatologic manifestations range from vitiligo to hyperpigmentation. The association of adrenal autoantibodies and vitiligo has made the latter a possible cutaneous marker for an autoimmune cause. The other cutaneous marker, hyperpigmentation, is...

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Bibliographic Details
Published in:	Cutis (New York, N.Y.) Vol. 36; no. 4; p. 317
Main Authors:	Mulligan, T M, Sowers, J R
Format:	Journal Article
Language:	English
Published:	United States 01-10-1985
Subjects:	Addison Disease - complications Addison Disease - immunology Addison Disease - metabolism Adrenocorticotropic Hormone - secretion Aged Humans Hydrocortisone - deficiency Male Melanocyte-Stimulating Hormones - secretion Pigmentation Disorders - etiology Pro-Opiomelanocortin - secretion Vitiligo - etiology
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Summary:	Addison's disease is an uncommon disorder whose dermatologic manifestations range from vitiligo to hyperpigmentation. The association of adrenal autoantibodies and vitiligo has made the latter a possible cutaneous marker for an autoimmune cause. The other cutaneous marker, hyperpigmentation, is now more clearly understood on the basis of a prohormone common to both adrenocorticotrophic hormone (ACTH) and melanocyte-stimulating hormone (MSH).
ISSN:	0011-4162