Aspergillus coronary embolization causing acute myocardial infarction

An increased frequency of disseminated aspergillosis has been observed in the last decade, mostly occurring in immunocompromised patients including the bone marrow transplant population. Cardiac involvement by Aspergillus remains rare. We report the clinical and postmortem findings of an unusual cas...

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Bibliographic Details
Published in:	Bone marrow transplantation (Basingstoke) Vol. 3; no. 3; p. 229
Main Authors:	Laszewski, M, Trigg, M, de Alarcon, P, Giller, R
Format:	Journal Article
Language:	English
Published:	England 01-05-1988
Subjects:	Aspergillosis - complications Aspergillosis - etiology Aspergillosis - pathology Bone Marrow Transplantation Child Coronary Disease - complications Coronary Thrombosis - complications Coronary Thrombosis - etiology Coronary Thrombosis - pathology Humans Male Myocardial Infarction - etiology Myocardial Infarction - pathology Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - therapy
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Summary:	An increased frequency of disseminated aspergillosis has been observed in the last decade, mostly occurring in immunocompromised patients including the bone marrow transplant population. Cardiac involvement by Aspergillus remains rare. We report the clinical and postmortem findings of an unusual case of Aspergillus pancarditis in a 7-year-old bone marrow transplant patient with Aspergillus embolization to the coronary arteries leading to a massive acute myocardial infarction. This case suggests that myocardial injury secondary to disseminated aspergillosis should be included in the differential diagnosis of chest pain in the immunocompromised pediatric patient.
ISSN:	0268-3369