The epidemiology of hemorrhage from the upper gastrointestinal tract in the mid-nineties--has anything changed?

• Published in: Hepato-gastroenterology Vol. 45; no. 24; p. 2228
• Main Author: Skok, P
• Format: Journal Article
• Language: English
• Published: Greece 01-11-1998
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Causality; Child; Child, Preschool; Cross-Sectional Studies; Female; Gastrointestinal Hemorrhage - epidemiology; Gastrointestinal Hemorrhage - etiology; Humans; Incidence; Male; Middle Aged; Peptic Ulcer Hemorrhage - epidemiology; Peptic Ulcer Hemorrhage - etiology; Retrospective Studies; Risk Factors
• ISSN: 0172-6390

Gastrointestinal hemorrhage is a frequent medical problem and a significant cause of morbidity and mortality. The aim of this retrospective analysis, which was carried out at our institution, was to establish the causes of hemorrhage from the upper digestive tract during a 3-year period.
The retrospective study includes those patients in which urgent endoscopic investigations of the upper digestive tract were carried out between 1 January 1994 and 31 December 1996.
2150 patients were investigated: 797 women and 1353 men. The average age of our patients was 57 years (a 3-97 year span, SD+/-17). In 665 patients (35.8%), endoscopic investigation of the upper digestive tube revealed signs of acute hemorrhage or traces of previous hemorrhage. Endoscopic hemostasis was carried out in 577 cases (31.1%). Sequelae of ulcer disease were the cause of hemorrhage in 46.1% of investigated patients. Frequent causes of hemorrhage were also inflammatory, hemorrhagically-erosive changes of the gastric and duodenal mucosa (21.9%), ruptured esophageal varices (9.4%), and esophageal reflux disease (8.0%). In 13.6% of patients the cause of hemorrhage did not lie in the upper digestive tract. In 50.3% of cases the gastrointestinal hemorrhage manifested itself by the discharge of melenic feces, and in 33.1% by hematemesis. 47.2% of our patients were aged over 60.
Also in our society sequelae of ulcer disease are the most significant cause of gastrointestinal hemorrhage. Hemorrhages are frequent in elderly patients who usually have accompanying diseases.