Familial Kaposi's sarcoma

Familial cases of Kaposi's sarcoma are exceedingly rare. We identified an 85-year-old man with Kaposi's sarcoma. Multiple lesions were present on the feet. Previously, the man's 84-year-old sister presented with similar lesions on the lower extremity. Both siblings were lifelong resid...

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Bibliographic Details
Published in:	Cutis (New York, N.Y.) Vol. 57; no. 4; p. 220
Main Authors:	Perniciaro, C, Gross, D J, White, Jr, J W, Adrian, R M
Format:	Journal Article
Language:	English
Published:	United States 01-04-1996
Subjects:	Aged Aged, 80 and over Female Foot Humans Male Sarcoma, Kaposi - genetics Sarcoma, Kaposi - pathology Sarcoma, Kaposi - therapy Skin Neoplasms - genetics Skin Neoplasms - pathology Skin Neoplasms - therapy
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Summary:	Familial cases of Kaposi's sarcoma are exceedingly rare. We identified an 85-year-old man with Kaposi's sarcoma. Multiple lesions were present on the feet. Previously, the man's 84-year-old sister presented with similar lesions on the lower extremity. Both siblings were lifelong residents of the United States and were of English/German descent. Neither had risk factors for infection with human immunodeficiency virus (HIV). On histologic examination, lesions in both patients demonstrated vascular slits, hemorrhage, and dense aggregates of spindle cells within the dermis.
ISSN:	0011-4162