Haemoglobin C gene in south eastern Nigeria

Haemoglobin C gene in south eastern Nigeria

Haemoglobin C (Hb C) is very rare in eastern Nigeria (east of River Niger). Isolated cases have been reported. The incidence is however as high as 6% in western Nigeria. This study was undertaken to locate the isolated cases with a view to determining their origin. Hb electrophoresis was performed o...

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Bibliographic Details
Published in:East African medical journal Vol. 73; no. 9; p. 566
Main Authors: Usanga, E A, Andy, J J, Ekanem, A D, Udoh, E A, Udoh, A E
Format: Journal Article
Language:English
Published: Kenya 01-09-1996
Subjects:
Adolescent
Adult
Blood Protein Electrophoresis
Child
Genotype
Hemoglobin C Disease - blood
Hemoglobin C Disease - epidemiology
Hemoglobin C Disease - genetics
Humans
Incidence
Middle Aged
Nigeria - epidemiology
Occupations
Population Surveillance
Residence Characteristics
Nigeria
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Summary:Haemoglobin C (Hb C) is very rare in eastern Nigeria (east of River Niger). Isolated cases have been reported. The incidence is however as high as 6% in western Nigeria. This study was undertaken to locate the isolated cases with a view to determining their origin. Hb electrophoresis was performed on 4,263 subjects in Akwa Ibom State in south eastern region of Nigeria. The subjects were selected from all the local government areas of the state and were aged 15 years and above. They comprised secondary school children, civil servants, farmers and fishermen. The results revealed complete absence of Hb C from the upland population whereas this was present in the fishing settlement population (6 or 0.4% Hb AC and one or 0.07% Hb SC subjects). The possible entry points of Hb C gene into south eastern Nigeria is discussed.
ISSN:0012-835X