Vitamin K1 binding protein in milk

Cow's milk has been shown to contain a protein complex which is able to bind vitamin K1 in a reversible manner. This binding property has been investigated by the celite method which consists in creating a dynamic equilibrium between the adsorbent, the celite and the protein complex for the lig...

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Bibliographic Details
Published in:International journal for vitamin and nutrition research Vol. 57; no. 2; p. 145
Main Authors: Fournier, B, Leclercq, M, Audigier-Petit, C, Letoublon, R, Got, R, Frot-Coutaz, J
Format: Journal Article
Language:English
Published: Switzerland 1987
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Summary:Cow's milk has been shown to contain a protein complex which is able to bind vitamin K1 in a reversible manner. This binding property has been investigated by the celite method which consists in creating a dynamic equilibrium between the adsorbent, the celite and the protein complex for the ligand (vitamin K1). Based on competition experiment, the binding is specific and the vitamin K1 binding protein complex has a molecular weight equal to or higher than 7.5 X 10(2) KD.
ISSN:0300-9831