HIV-enteropathy and bile acid malabsorption: response to cholestyramine

Chronic diarrhea and weight loss are common in patients with AIDS. We report on an AIDS patient with chronic diarrhea, steatorrhea, and marked weight loss. A 75SeHCAT test demonstrated that the diarrhea was mainly due to bile acid malabsorption. Therapy with cholestyramine dramatically reduced bowel...

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Bibliographic Details
Published in:	The American journal of gastroenterology Vol. 90; no. 11; p. 2051
Main Authors:	Steuerwald, M, Bucher, H C, Müller-Brand, J, Götze, M, Roser, H W, Gyr, K
Format:	Journal Article
Language:	English
Published:	United States 01-11-1995
Subjects:	Adult AIDS-Related Opportunistic Infections - diagnosis Bile Acids and Salts - metabolism Cholestyramine Resin - therapeutic use HIV Enteropathy - complications HIV Enteropathy - drug therapy HIV Enteropathy - metabolism Humans Malabsorption Syndromes - complications Malabsorption Syndromes - diagnosis Malabsorption Syndromes - drug therapy Malabsorption Syndromes - metabolism Male Selenium Radioisotopes Taurocholic Acid - analogs & derivatives
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Summary:	Chronic diarrhea and weight loss are common in patients with AIDS. We report on an AIDS patient with chronic diarrhea, steatorrhea, and marked weight loss. A 75SeHCAT test demonstrated that the diarrhea was mainly due to bile acid malabsorption. Therapy with cholestyramine dramatically reduced bowel movements and led to significant reversal of weight loss.
ISSN:	0002-9270
DOI:	10.1111/j.1572-0241.1995.tb10194.x