Correlates of plasma atrial natriuretic peptide levels in renal transplant recipients

Correlates of plasma atrial natriuretic peptide levels in renal transplant recipients

Plasma atrial natriuretic peptide (ANP) levels were measured with a radio-immunoassay in 56 patients, 3 weeks to 16 1/2 years after renal transplantation. At the time of the study their renal function was stable, with creatinine clearances ranging from 10 to 101 ml/min. Plasma ANP levels ranged from...

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Bibliographic Details
Published in:Clinical nephrology Vol. 31; no. 3; p. 146
Main Authors: Doorenbos, C J, Daha, M R, van Brummelen, P
Format: Journal Article
Language:English
Published: Germany 01-03-1989
Subjects:
Adolescent
Adult
Age Factors
Aged
Atrial Natriuretic Factor - blood
Blood Pressure
Creatinine - urine
Female
Humans
Kidney Transplantation
Male
Middle Aged
Sodium - urine
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Summary:Plasma atrial natriuretic peptide (ANP) levels were measured with a radio-immunoassay in 56 patients, 3 weeks to 16 1/2 years after renal transplantation. At the time of the study their renal function was stable, with creatinine clearances ranging from 10 to 101 ml/min. Plasma ANP levels ranged from 1 to 941 pg/ml and were found to correlate positively with both age and systolic blood pressure. Moreover, a negative correlation was found between plasma ANP levels and creatinine clearance. We conclude that in renal transplant recipients neither renal denervation nor the use of immunosuppressive therapy abolishes the influence of age, systolic blood pressure and renal function on the plasma levels of ANP.
ISSN:0301-0430