Ultrastructure of synapses in cerebral cortex layer i in rats with low and high resistance to hypoxia

Quantitative analysis of synapses in layer I of the sensorimotor cortex in rats with low resistance to hypoxia revealed pronounced changes in the number of synaptic vesicles docked at the presynaptic membrane in active synaptic zones under conditions of acute hypobaric hypoxia. In high-resistant ani...

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Bibliographic Details
Published in:	Bulletin of experimental biology and medicine Vol. 131; no. 5; pp. 499 - 501
Main Authors:	Svinov, M M, Zakharova, E I, Kositsyn, N S
Format:	Journal Article
Language:	English
Published:	United States Springer Nature B.V 01-05-2001
Subjects:	Animals Cerebral Cortex - ultrastructure Hypoxia Male Microscopy, Electron Rats Synapses - ultrastructure
Online Access:	Get full text
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Summary:	Quantitative analysis of synapses in layer I of the sensorimotor cortex in rats with low resistance to hypoxia revealed pronounced changes in the number of synaptic vesicles docked at the presynaptic membrane in active synaptic zones under conditions of acute hypobaric hypoxia. In high-resistant animals the number of docked synaptic vesicles under these conditions remained unchanged. In was hypothesized that high sensitivity to hypoxia in low-resistant rats is determined by high reactivity of the synaptic transmission system.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0007-4888 1573-8221
DOI:	10.1023/A:1017952721477