Alteration in Resting-State Brain Activity in Stroke Survivors After Repetitive Finger Stimulation

This quasi-experimental study examined the effect of repetitive finger stimulation on brain activation in eight stroke and seven control subjects, measured by quantitative electroencephalogram. We applied 5 mins of 2-Hz repetitive bilateral index finger transcutaneous electrical nerve stimulation an...

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Bibliographic Details
Published in:American journal of physical medicine & rehabilitation Vol. 103; no. 5; p. 395
Main Authors: He, Dorothy, Sikora, William A, James, Shirley A, Williamson, Jordan N, Lepak, Louis V, Cheema, Carolyn F, Sidorov, Evgeny, Li, Sheng, Yang, Yuan
Format: Journal Article
Language:English
Published: United States 01-05-2024
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Summary:This quasi-experimental study examined the effect of repetitive finger stimulation on brain activation in eight stroke and seven control subjects, measured by quantitative electroencephalogram. We applied 5 mins of 2-Hz repetitive bilateral index finger transcutaneous electrical nerve stimulation and compared differences pre- and post-transcutaneous electrical nerve stimulation using quantitative electroencephalogram metrics delta/alpha ratio and delta-theta/alpha-beta ratio. Between-group differences before and after stimulation were significantly different in the delta/alpha ratio ( z = -2.88, P = 0.0040) and the delta-theta/alpha-beta ratio variables ( z = -3.90 with P < 0.0001). Significant decrease in the delta/alpha ratio and delta-theta/alpha-beta ratio variables after the transcutaneous electrical nerve stimulation was detected only in the stroke group (delta/alpha ratio diff = 3.87, P = 0.0211) (delta-theta/alpha-beta ratio diff = 1.19, P = 0.0074). The decrease in quantitative electroencephalogram metrics in the stroke group may indicate improved brain activity after transcutaneous electrical nerve stimulation. This finding may pave the way for a future novel therapy based on transcutaneous electrical nerve stimulation and quantitative electroencephalogram measures to improve brain recovery after stroke.
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ISSN:1537-7385
1537-7385
DOI:10.1097/PHM.0000000000002393