Acute Hematogenous Osteomyelitis in Children: Pathogenesis, Diagnosis, and Treatment

• Published in: The Orthopedic clinics of North America Vol. 48; no. 2; pp. 199 - 208
• Main Authors: Funk, Shawn S, Copley, Lawson A B
• Format: Journal Article
• Language: English
• Published: United States 01-04-2017
• Subjects: Bacteremia - complications; Bacteremia - diagnosis; Bacteremia - prevention & control; Child; Disease Management; Humans; Osteomyelitis - blood; Osteomyelitis - diagnosis; Osteomyelitis - microbiology; Osteomyelitis - therapy; Treatment; Children; Diagnosis; Pathogenesis; Acute hematogenous osteomyelitis
• ISSN: 1558-1373
• DOI: 10.1016/j.ocl.2016.12.007

Acute hematogenous osteomyelitis (AHO) in children is an ideal condition to study due to its representation of a wide spectrum of disorders that comprise pediatric musculoskeletal infection. Proper care for children with AHO is multidisciplinary and collaborative. AHO continues to present a significant clinical challenge due to evolving epidemiology and complex pathogenesis. A guideline-driven, multidisciplinary approach has been introduced and shown to effectively reduce hospital stay, improve the timing and selection of empirical antibiotic administration, reduce delay to initial MRI, reduce the rate of readmission, and shorten antibiotic duration.