Cardiometabolic effects of weight loss

The prevalence of overweight and obesity, and, consequently, associated comorbidities, is increasing significantly worldwide. The guidelines recommend a percentage of weight loss> 5% to achieve beneficial effects on metabolic comorbidities associated with obesity. Furthermore, greater weight loss...

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Bibliographic Details
Published in:	Atención primaria Vol. 56; no. 10; p. 102953
Main Authors:	Genua, Idoia, Sardà, Helena, Pérez, Antonio
Format:	Journal Article
Language:	Spanish
Published:	Spain 01-10-2024
Subjects:	Bariatric Surgery Cardiovascular Diseases - etiology Cardiovascular Diseases - prevention & control Humans Obesity - complications Obesity - metabolism Weight Loss Inflamación Obesidad Obesity Cardiovascular risk factors Factores de riesgo cardiovascular Dislipemia Dyslipidemia Pérdida de peso Weight loss Inflammation Diabetes
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Summary:	The prevalence of overweight and obesity, and, consequently, associated comorbidities, is increasing significantly worldwide. The guidelines recommend a percentage of weight loss> 5% to achieve beneficial effects on metabolic comorbidities associated with obesity. Furthermore, greater weight losses (> 10%) produce more significant improvements, and may even produce remission of some of these comorbidities. In this chapter, we review the evidence of the effect of weight loss through different strategies (lifestyle intervention, pharmacological treatment, or bariatric surgery) on the main cardiometabolic pathologies associated with excess adipose tissue (type 2 diabetes, high blood pressure, dyslipidemia, metabolic dysfunction-associated steatotic liver disease, inflammation, cardiovascular diseases, and mortality).
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23
ISSN:	1578-1275 1578-1275
DOI:	10.1016/j.aprim.2024.102953