Dyslipidemia and suicidal risk in patients with psychiatric disorders

• Published in: Encéphale Vol. 44; no. 4; p. 315
• Main Authors: Messaoud, A, Mensi, R, Mhalla, A, Hallara, I, Neffati, F, Douki, W, Najjar, M F, Gaha, L
• Format: Journal Article
• Language: French
• Published: France 01-09-2018
• Subjects: Adult; Cholesterol - blood; Dyslipidemias - complications; Dyslipidemias - epidemiology; Female; Humans; Lipids - blood; Male; Mental Disorders - blood; Mental Disorders - complications; Mental Disorders - epidemiology; Middle Aged; Risk Factors; Schizophrenia - blood; Schizophrenia - complications; Schizophrenia - epidemiology; Self-Injurious Behavior - blood; Self-Injurious Behavior - complications; Self-Injurious Behavior - epidemiology; Suicidal Ideation; Suicide - psychology; Suicide - statistics & numerical data; Suicidal risk; Dyslipidémie; Risque suicidaire; Pathologies psychiatriques; Psychiatric pathology; Dyslipidemia
• ISSN: 0013-7006
• DOI: 10.1016/j.encep.2017.03.008

The aim of this work is to study the association between dyslipidemia and suicidal risk in patients with psychiatric pathology. Our study has involved 155 patients suffering from major depressive disorder and 124 schizophrenic patients aged 40.58±12.16 and 43.43±10.60 years, respectively. Total cholesterol (TC), triglycerides (TG) and HDL-c were determined by enzymatic methods, LDL-c was calculated by the Friedewald formula. Plasma cholesterol level was significantly lower among suicidal schizophrenic or depressive patients. There were no significant differences in the others lipid levels. The results of our study suggest that total cholesterol values less than 3.59mmol/L could be an indicator of suicide vulnerability in patients with schizophrenia or major depressive disorder.