Leiomyosarcoma of the inferior nasal concha: a case report and literature review

• Published in: B-ENT (Leuven) Vol. 8; no. 3; p. 213
• Main Authors: d'Adesky, C, Duterme, J P, Lejeune, D, Mehta, R, Chaikh, A, Castadot, P, Duchateau, J P
• Format: Journal Article
• Language: English
• Published: Belgium 01-01-2012
• Subjects: Aged; Diagnosis, Differential; Female; Follow-Up Studies; Humans; Leiomyosarcoma - diagnosis; Leiomyosarcoma - radiotherapy; Magnetic Resonance Imaging; Nose Neoplasms - diagnosis; Nose Neoplasms - radiotherapy; Radiotherapy, Conformal; Tomography, X-Ray Computed; Turbinates
• ISSN: 1781-782X

Leiomyosarcomas (LMSs) of the sinonasal tracts are rarely reported. We present a case of an LMS of the left inferior nasal concha, and discuss the management options with review of the literature. A 72-year-old female patient presented with epistaxis. Clinical examination and medical imaging showed a tumour arising from the left inferior nasal concha. An endoscopic resection was performed. Anatomopathological and immunohistochemical analyses revealed the tumour to be a grade 3 LMS with uncertain posterior margins. The patient was a Jehovah's Witness and refused more radical surgical resection due to religious beliefs; therefore, adjuvant conformal radiotherapy (60 Gy) was performed. LMS of the nasal cavity is a rare and locally aggressive tumour with a high tendency of recurrence, requiring radical surgical resection and long-term follow-up. The prognosis of a nasal cavity LMS is better than that of an LMS located in the paranasal sinuses.