Structure of peripheral blood platelets surface in patients with amyotrophic lateral sclerosis and multiple sclerosis

Using scanning electronic microscopy of peripheral blood platelets in 32 patients with amyotrophic lateral sclerosis (ALS) and 6 patients with multiple sclerosis (MS), platelets activation, emerging in pseudopodiums formation, aggregation and lysis, was found. Platelets activation was more pronounce...

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Bibliographic Details
Published in:	Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova Vol. 105; no. 3; p. 40
Main Authors:	Kiktenko, A I, Zlobina, G P, Brusov, O S, Zakharova, M N
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 2005
Subjects:	Amyotrophic Lateral Sclerosis - blood Blood Platelets - physiology Blood Platelets - ultrastructure Data Interpretation, Statistical Humans Microscopy, Electron, Scanning Multiple Sclerosis - blood Platelet Aggregation Surface Properties
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Summary:	Using scanning electronic microscopy of peripheral blood platelets in 32 patients with amyotrophic lateral sclerosis (ALS) and 6 patients with multiple sclerosis (MS), platelets activation, emerging in pseudopodiums formation, aggregation and lysis, was found. Platelets activation was more pronounced in ALS than in MS. It was most markedly seen for quantitative evaluation of the above traits. The features of platelet activation found in the study support the evidence for considering ALS as a systemic disorder being characterized by a broad spectrum of alterations of biological processes.
ISSN:	1997-7298