Immunohistochemical studies in diagnosis of the uncommon cases of tumours of the central nervous system

Immunohistochemical studies in diagnosis of the uncommon cases of tumours of the central nervous system

There is a growing evidence that tumoursof the central nervous system (CNS) exhibit some immunophenotypic aberrations pointing to the multipotential cell differentiation. However, the immunohistochemistry remains still very helpful in differential diagnosis and nosologic classification of the CNS ne...

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Bibliographic Details
Published in:Folia histochemica et cytobiologica Vol. 40; no. 2; p. 207
Main Authors: Taraszewska, A, Matyja, E
Format: Journal Article
Language:English
Published: Poland 2002
Subjects:
Adult
Astrocytoma - diagnosis
Astrocytoma - pathology
Biomarkers, Tumor
Central Nervous System Neoplasms - diagnosis
Central Nervous System Neoplasms - pathology
Cerebral Ventricles - pathology
Female
Glioma - diagnosis
Glioma - pathology
Humans
Immunohistochemistry
Male
Middle Aged
Neurocytoma - diagnosis
Neurocytoma - pathology
Neuroectodermal Tumors - diagnosis
Neuroectodermal Tumors - pathology
Spinal Cord - pathology
Tissue Embedding
Tissue Fixation
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Summary:There is a growing evidence that tumoursof the central nervous system (CNS) exhibit some immunophenotypic aberrations pointing to the multipotential cell differentiation. However, the immunohistochemistry remains still very helpful in differential diagnosis and nosologic classification of the CNS neoplasms. The purpose of this paper is to present the immunomorphological pattern of some rare neoplasms of neuroepithelial origin that over last years were recognised and classified as new clinico-pathological entities. Histological and immuniohistochemical features of three cases including pleomorphic xanthoastrocytoma, chordoid glioma and central neurocytoma are reported with special references to immunohistochemical differentiation of these neoplasmswith other tumours of similar morphology but different histogenesis.
ISSN:0239-8508