Metastatic cervical carcinoma to the thyroid gland: a case report and review of the literature

Although metastases within the thyroid gland are rare, they are not as infrequent as generally believed. Asymptomatic breast, lung, and renal cell carcinomas may metastasize to the thyroid. When they become symptomatic, diagnosis relies upon fine needle aspiration cytology. We report the case of a s...

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Bibliographic Details
Published in:	The Yale journal of biology & medicine Vol. 79; no. 3-4; pp. 165 - 168
Main Authors:	Karapanagiotou, Elena, Saif, Muhammad Wasif, Rondoyianni, Dimitra, Markaki, Sofia, Alamara, Christina, Kiagia, Maria, Pantazopoulos, Kosmas, Tzannou, Ifigenia, Syrigos, Kostas
Format:	Journal Article
Language:	English
Published:	United States Yale Journal of Biology and Medicine 01-12-2006
Series:	Cancer issue
Subjects:	Abdomen Aged Biopsy Bronchoscopy Cancer therapies Carcinoma, Squamous Cell - drug therapy Carcinoma, Squamous Cell - pathology Case Report Case reports Cellular biology Cervical cancer Cervical carcinoma Cervix Chemotherapy Combined Modality Therapy Cytology Diagnosis Female Humans Literature reviews Lung carcinoma Lymphatic system Malignancy Medical prognosis Medical research Metastases Metastasis Neoplasm Metastasis Patients Quality of life Radiation therapy Renal cell carcinoma Thyroid Thyroid gland Thyroid Gland - pathology Thyroid Neoplasms - diagnosis Thyroid Neoplasms - secondary Thyroid Neoplasms - therapy Treatment Outcome Tumors Uterine Cervical Neoplasms - pathology Uterine Cervical Neoplasms - therapy
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Summary:	Although metastases within the thyroid gland are rare, they are not as infrequent as generally believed. Asymptomatic breast, lung, and renal cell carcinomas may metastasize to the thyroid. When they become symptomatic, diagnosis relies upon fine needle aspiration cytology. We report the case of a squamous cell cervical cancer that presented metastatic lesions to the thyroid gland four years after the initial diagnosis. The procedures used to confirm the diagnosis, stage, and subsequently manage the patient are described. We present both a review of the necessary clinical investigation and the therapeutic options open to these patients. We conclude that patients who present swelling or palpable nodules in the thyroid side and have a history of a previous malignancy must be considered for metastatic disease.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	0044-0086 1551-4056