The newer cephalosporins. Aztreonam and imipenem

Many of the antimicrobial agents described here exhibit great advances over older drugs in terms of antimicrobial spectrum, clinical utility, and, sometimes, safety. The newer cephalosporins are useful for treatment of many common outpatient and inpatient infections. Aztreonam provides excellent cov...

Full description

Saved in:

Bibliographic Details
Published in:	Infectious disease clinics of North America Vol. 9; no. 3; p. 687
Main Authors:	Ennis, D M, Cobbs, C G
Format:	Journal Article
Language:	English
Published:	United States 01-09-1995
Subjects:	Aztreonam - pharmacology Aztreonam - therapeutic use Cephalosporins - pharmacology Cephalosporins - therapeutic use Drug Resistance, Microbial Humans Imipenem - pharmacology Imipenem - therapeutic use Monobactams - therapeutic use Thienamycins - therapeutic use
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Many of the antimicrobial agents described here exhibit great advances over older drugs in terms of antimicrobial spectrum, clinical utility, and, sometimes, safety. The newer cephalosporins are useful for treatment of many common outpatient and inpatient infections. Aztreonam provides excellent coverage against a broad range of aerobic gram-negative bacteria, without the toxicity associated with aminoglycosides. Imipenem exhibits activity against an impressive array of pathogens. These antimicrobials are expensive, however, and some offer no advantages over older agents. Finally, all--including imipenem--are faced with increasing resistance of bacteria.
ISSN:	0891-5520