Bone marrow patterns in chronic lymphocytic leukaemia related to various clinical and haematological findings. A preliminary report

In a retrospective study of 55 CLL cases subjected to bone-marrow biopsy, the histological pattern of the bone-marrow was correlated to the clinical and haematological data. Instead of the four histological patterns described by Rozman et al., five patterns have been established. The clinical stagin...

Full description

Saved in:

Bibliographic Details
Published in:	Haematologia Vol. 18; no. 2; p. 115
Main Authors:	Gingold, N, Dosius, L, Berceanu, S
Format:	Journal Article
Language:	English
Published:	Netherlands 1985
Subjects:	Adult Aged Biopsy Bone Marrow - pathology Female Hematopoiesis Humans Leukemia, Lymphoid - blood Leukemia, Lymphoid - classification Leukemia, Lymphoid - pathology Leukemia, Lymphoid - physiopathology Male Middle Aged Prognosis
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	In a retrospective study of 55 CLL cases subjected to bone-marrow biopsy, the histological pattern of the bone-marrow was correlated to the clinical and haematological data. Instead of the four histological patterns described by Rozman et al., five patterns have been established. The clinical staging according to the Montserrat score, compared with the bone-marrow pattern, showed a good correlation, when maintenance or replacement of normal haematopoiesis was considered. The bone-marrow pattern with maintained haematopoiesis was predicting a favourable clinical correlation; those with replaced haematopoiesis corresponded to a poor prognosis. The correlation is a useful index of severity and prognosis of CLL.
ISSN:	0017-6559