N-acetyltransferase phenotype of patients with cancer of the larynx

In the present paper N-acetyltransferase phenotype has been evaluated in 128 patients with cancer of the larynx. Out of 128 patients, 86.7% were smokers. The corresponding control group consisted of 106 men who did not suffer from neoplastic diseases. 83.6% of the patients were slow acetylators. Thi...

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Bibliographic Details
Published in:	Neoplasma Vol. 34; no. 4; pp. 481 - 484
Main Authors:	Drózdz, M, Gierek, T, Jendryczko, A, Pilch, J, Piekarska, J
Format:	Journal Article
Language:	English
Published:	Slovakia 1987
Subjects:	Acetylation Acetyltransferases - genetics Adult Carcinoma, Squamous Cell - enzymology Carcinoma, Squamous Cell - genetics Humans Laryngeal Neoplasms - enzymology Laryngeal Neoplasms - genetics Middle Aged Phenotype Smoking - metabolism
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Summary:	In the present paper N-acetyltransferase phenotype has been evaluated in 128 patients with cancer of the larynx. Out of 128 patients, 86.7% were smokers. The corresponding control group consisted of 106 men who did not suffer from neoplastic diseases. 83.6% of the patients were slow acetylators. This is significantly different from the frequency of 60.3% of slow acetylators observed in the control group. The slow acetylators exhibited a greater susceptibility to the cancer of the larynx.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0028-2685