Malignant Zollinger-Ellison syndrome. Stabilization of liver metastasis after gastrectomy with resection of primary tumor

A case of malignant gastrinoma of the jejunum and jejunal mesentery, with findings of metastasis in the liver was studied. Tumor resection and remnant gastrectomy, as well as liver biopsy, were performed. Of all the tumors removed, the metastatic tumor had the lowest gastrin content, which was 1.5 t...

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Bibliographic Details
Published in:	The American surgeon Vol. 56; no. 6; p. 360
Main Authors:	Katoh, H, Yabana, T, Yachi, A, Tanabe, T
Format:	Journal Article
Language:	English
Published:	United States 01-06-1990
Subjects:	Adult Follow-Up Studies Gastrectomy Gastrins - analysis Humans Jejunal Neoplasms - surgery Liver Neoplasms - secondary Liver Neoplasms - surgery Male Time Factors Zollinger-Ellison Syndrome - surgery
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Summary:	A case of malignant gastrinoma of the jejunum and jejunal mesentery, with findings of metastasis in the liver was studied. Tumor resection and remnant gastrectomy, as well as liver biopsy, were performed. Of all the tumors removed, the metastatic tumor had the lowest gastrin content, which was 1.5 times that found in normal human antral mucosa. The gastrin distribution was of four peaks and one peak for the main tumor, versus two peaks for the metastatic tumor in which G17 was the main component. Seven years after the operation, computed tomography (CT) scan indicated there was stabilization of the liver metastasis, and now, ten years after the total gastrectomy, the patient is well and working full-time. Such an analysis can be of value in determining the prognosis in cases of malignant gastrinoma with liver metastasis.
ISSN:	0003-1348