Effects of intramedullary injection of methiodal and lidocaine on spinal cords of dogs

A solution of methiodal sodium (20%) and lidocaine HCl (0.20%) was given by intramedullary injection into the lumbar spinal cords of 12 anesthetized dogs (group I). Two control groups of 12 dogs each were subjected to needle placement only or were given 5% dextrose. The results showed that both solu...

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Bibliographic Details
Published in:	American journal of veterinary research Vol. 36; no. 10; p. 1529
Main Authors:	Parker, A J, Cusick, P K, Stowater, J L, Park, R D
Format:	Journal Article
Language:	English
Published:	United States 01-10-1975
Subjects:	Animals Dog Diseases - chemically induced Dog Diseases - pathology Dogs Female Injections Lidocaine - administration & dosage Lidocaine - adverse effects Male Mesylates - administration & dosage Mesylates - adverse effects Proprioception Spinal Cord - pathology Spinal Cord Diseases - chemically induced Spinal Cord Diseases - pathology Spinal Cord Diseases - veterinary
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Summary:	A solution of methiodal sodium (20%) and lidocaine HCl (0.20%) was given by intramedullary injection into the lumbar spinal cords of 12 anesthetized dogs (group I). Two control groups of 12 dogs each were subjected to needle placement only or were given 5% dextrose. The results showed that both solutions given by intramedullary injection caused severe spinal cord malacia and cavitation in 2 group I dogs and in 1 group III dog.
ISSN:	0002-9645