Advanced lung cancer with recurrence of liver and tracheal metastases responsive to multimodality therapy - a case report

• Published in: Gan to kagaku ryoho Vol. 41; no. 12; p. 2047
• Main Authors: Higaki, Naozumi, Nakane, Shigeru, Uemura, Hisashi, Okada, Kaoru, Miyake, Yasuhiro, Murakami, Masakazu, Hayashida, Hirohito, Oka, Yoshio, Kusakabe, Yoshito, Tsuruta, Naotoshi, Tetsumoto, Satoshi, Saito, Yoshiyuki, Niju, Takashi, Ikeda, Toshiyuki, Nezu, Riichiro
• Format: Journal Article
• Language: Japanese
• Published: Japan 01-11-2014
• Subjects: Aged; Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Carcinoma, Squamous Cell - secondary; Carcinoma, Squamous Cell - therapy; Combined Modality Therapy; Humans; Liver Cirrhosis, Alcoholic - complications; Liver Neoplasms - secondary; Liver Neoplasms - therapy; Lung Neoplasms - pathology; Lung Neoplasms - surgery; Lung Neoplasms - therapy; Male; Pulmonary Disease, Chronic Obstructive - complications; Recurrence; Tracheal Neoplasms - secondary; Tracheal Neoplasms - therapy; Treatment Outcome
• ISSN: 0385-0684

We report a case of advanced lung cancer with recurrence of liver and tracheal metastases that were responsive to multimodality therapy. The patient was a 77-year-old man who suffered from advanced lung cancer with chronic obstructive pulmonary disease (COPD) and alcohol-induced liver cirrhosis. The primary lung cancer was surgically resected. Eight months after resection of the primary lung cancer, a solitary liver tumor appeared and hepatic resection was performed. Histological findings showed that both the primary lung tumor and the solitary liver tumor were squamous cell carcinoma (SCC). Subsequently, he developed a recurrence in his trachea 8 months after hepatic resection. Radiotherapy, endobronchial argon plasma coagulation (APC), and systemic chemotherapy were administered. The tracheal tumor remained stable without any liver metastasis for 25 months.