Comparative analysis of abnormal Pap smear and the results of histopathological examination of specimens from the cervix of the programme in-depth diagnosis cervical cancer conducted at the of Operational Gynecology Department ICZMP in Lodz

• Published in: Ginekologia polska Vol. 81; no. 11; pp. 828 - 833
• Main Authors: Kulig, Bartosz, Łukaszek, Stanisław, Brucka, Aleksandra, Kałuzyński, Andrzej, Kamer-Bartosińska, Anna, Szyłło, Krzysztof
• Format: Journal Article
• Language: Polish
• Published: Poland Wydawnictwo Via Medica 01-11-2010
• Subjects: Adult; Biopsy; Cervical cancer; Cervical Intraepithelial Neoplasia - pathology; Colposcopy - statistics & numerical data; Early Detection of Cancer - statistics & numerical data; Female; Humans; Mass Screening - organization & administration; Mass Screening - statistics & numerical data; Medical screening; Middle Aged; Outpatient Clinics, Hospital - organization & administration; Pap smear; Papanicolaou Test; Poland - epidemiology; Uterine Cervical Dysplasia - pathology; Uterine Cervical Neoplasms - diagnosis; Uterine Cervical Neoplasms - prevention & control; Vaginal Smears - methods; Vaginal Smears - statistics & numerical data; Women's Health; Poland
• ISSN: 0017-0011; 2543-6767

Cervical Cancer Screening Program has been operational in Poland for over four years. Colposcopy and guided biopsy methods constitute an essential part of population-based screening, enable stating right diagnosis and planning treatment procedures.
The aim of the following study was to analyse the diagnostic acuity of cyto- and histopathological examination.
We examined 510 patients with the following result of cytological smear: ASCUS--265 women (51.96%), LSIL--167 cases (35.75%), HSIL--78 women (15.29%). Complete agreement between cytological smear and guided biopsy histopathology was observed among 81.13% cases of ASCUS, in 88.02% of women with LSIL and in 76.92% cases with the diagnosis of HSIL. As with cytology-biopsy comparisons, discordant cases were significantly more frequent in the group with stated HSIL than among patients with the diagnosis of ASCUS or LSIL (p<0.001).
1. High cyto-histopathological accordance (82%) has been obtained, what is comparable with the data in literature. 2. The highest cyto- histopathological compatibility was obtained in the group of patients with LSIL--over 88%, and the lowest in the group of patients with HSIL--less than 77%. 3. Failure to confirm the histopathological diagnosis of cytological HSIL requires further molecular and morphological evaluation.