Carcinoma of the paranasal sinuses: results of treatment and some prognostic factors

• Published in: Strahlentherapie und Onkologie Vol. 168; no. 6; p. 322
• Main Authors: Budihna, M, Smid, L
• Format: Journal Article
• Language: English
• Published: Germany 01-06-1992
• Subjects: Adenocarcinoma - drug therapy; Adenocarcinoma - radiotherapy; Adenocarcinoma - surgery; Aged; Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Carcinoma, Adenoid Cystic - drug therapy; Carcinoma, Adenoid Cystic - radiotherapy; Carcinoma, Adenoid Cystic - surgery; Carcinoma, Squamous Cell - drug therapy; Carcinoma, Squamous Cell - radiotherapy; Carcinoma, Squamous Cell - surgery; Cobalt Radioisotopes - therapeutic use; Combined Modality Therapy; Ethmoid Sinus; Female; Fibrosarcoma - drug therapy; Fibrosarcoma - radiotherapy; Fibrosarcoma - surgery; Humans; Lymphoma - drug therapy; Lymphoma - radiotherapy; Lymphoma - surgery; Male; Maxillary Sinus Neoplasms - drug therapy; Maxillary Sinus Neoplasms - radiotherapy; Maxillary Sinus Neoplasms - surgery; Middle Aged; Paranasal Sinus Neoplasms - drug therapy; Paranasal Sinus Neoplasms - radiotherapy; Paranasal Sinus Neoplasms - surgery; Postoperative Care; Prognosis; Radiotherapy Dosage; Sphenoid Sinus
• ISSN: 0179-7158

Between 1979 and 1984, 46 patients, 23 males and 23 females, with carcinoma of the paranasal sinuses were treated at the Institute of Oncology in Ljubljana. A great majority of tumours were in an advanced stage of disease. 21 patients were operated on and all except one were postoperatively irradiated. Radiotherapy was the main treatment in the remaining 25 patients. 14 patients (30%) survived more than five years with no evidence of disease. Patients treated by a combination of surgery and postoperative radiotherapy survived significantly better (12/20-60%) than those treated by irradiation alone (2/25-8%), p less than 0.001. Patient's age and radicality of surgery also influenced the treatment results.