Atrioventricular block in granulomatosis with polyangiitis (Wegener's granulomatosis). Case report and review of literature

Granulomatosis with Polyangiitis (GPA), or Wegener's Granulomatosis, is an immunologically mediated systemic vasculitis of small and medium vessels, which commonly compromises the upper airway, lungs, and kidneys and is rarely associated with cardiac manifestations. Compromise of the cardiac co...

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Bibliographic Details
Published in:	Revista medíca de Chile Vol. 151; no. 8; p. 1088
Main Authors:	Changuan R, Luís, Asenjo G, René, Sanhueza G, Eduardo, Morris C, Raimundo, Ortíz O, Mario
Format:	Journal Article
Language:	Spanish
Published:	Chile 01-08-2023
Subjects:	Atrioventricular Block - etiology Electrocardiography Granulomatosis with Polyangiitis - complications Humans Male Middle Aged
Online Access:	Get full text
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Summary:	Granulomatosis with Polyangiitis (GPA), or Wegener's Granulomatosis, is an immunologically mediated systemic vasculitis of small and medium vessels, which commonly compromises the upper airway, lungs, and kidneys and is rarely associated with cardiac manifestations. Compromise of the cardiac conduction system is rare, and isolated cases of different degrees of atrioventricular block (AVB) have been described. We report a case of a 49-year-old male patient previously diagnosed with GPA 3 years ago, who presented to the emergency department with dyspnea, clinical signs of low output, bradycardia of 30/min, advanced second-degree AVB and complete left bundle branch block (LBBB) on the ECG. A literature review is presented, and we discuss the causes, evolution, and management of this GPA complication.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Review-5 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	0717-6163 0717-6163
DOI:	10.4067/s0034-98872023000801088