Uniliteral wheezes as the first clinical sign of a bronchial carcinoid

• Published in: Deutsche medizinische Wochenschrift (1946) Vol. 135; no. 9; p. 390
• Main Authors: Becher, U M, Kaminski, M, Grohe, C, Pabst, S, Juergens, U R, Wilhelm, K, Ahmadzadehfar, H, Majores, M, Büttner, R, Nickenig, G, Skowasch, D
• Format: Journal Article
• Language: German
• Published: Germany 01-03-2010
• Subjects: Airway Obstruction - etiology; Airway Obstruction - pathology; Airway Obstruction - surgery; Biopsy; Bronchoscopy; Carcinoid Tumor - diagnosis; Carcinoid Tumor - pathology; Carcinoid Tumor - surgery; Diagnosis, Differential; Dyspnea - etiology; Follow-Up Studies; Humans; Lung Neoplasms - diagnosis; Lung Neoplasms - pathology; Lung Neoplasms - surgery; Lymph Node Excision; Middle Aged; Pneumonectomy; Pulmonary Atelectasis - diagnosis; Respiratory Sounds - etiology; Tomography, X-Ray Computed
• ISSN: 1439-4413
• DOI: 10.1055/s-0030-1249175

A 58-years-old non-smoking woman presented at our Thoracic Centre with increasing exertional dyspnea and on examination was found to have wheezing and decreased breath sounds over the left lung.
Chest X-ray revealed an atelectasis of the left anterobasal lung segment. Computed tomography revealed a 3.5 cm mass at the left inferior lobe. Bronchioscopy showed a total occlusion of the segmental bronchus because of an endobronchial tumor. Histology of a biopsy showed the tumor to be a carcinoid. Staging by whole-body ocreotide scintigraphy showed no evidence of metastases.
The patient recovered quickly from resection of the left inferior lobe and radical lymphadenectomy. Two years later, she has remained free of symptoms and without evidence of recurrence.
Although rare (ca. 1.0 % of all primary lung tumors), the differential diagnosis of dyspnea and uniliteral wheezing should include a bronchial carcinoid. It is a potentially curable tumor, if detected and treated early. An interdisciplinary approach is pivotal to its perioperative management.