Febrile ulceronecrotic Mucha-Habermann disease in adult patient successfully treated with systemic corticosteroid

• Published in: Anais brasileiros de dermatología Vol. 85; no. 6; pp. 891 - 894
• Main Authors: Nassif, Priscila Wolf, Godoy, Deise Aparecida Santos, Nakandakari, Sadamitsu, Alves, Cinthia Janine Meira, Soares, Cleverson Teixeira
• Format: Journal Article
• Language: English; Portuguese
• Published: Brazil 01-11-2010
• Subjects: Glucocorticoids - therapeutic use; Herpes Simplex - drug therapy; Herpes Simplex - pathology; Humans; Male; Middle Aged; Pityriasis Lichenoides - drug therapy; Pityriasis Lichenoides - pathology; Prednisone - therapeutic use; Treatment Outcome
• ISSN: 1806-4841
• DOI: 10.1590/S0365-05962010000600018

The Febrile Ulceronecrotic Mucha-Habermann (FUMHD) disease is a rare variant of pityriasis lichenoides et varioliformis acuta (PLEVA). Its etiology still remains unknown and it is characterized by a sudden onset of ulceronecrotic skin lesions associated with systemic symptoms. It is reported here the case of a male patient with a sudden and acute evolution of macules and papules, ulceronecrotic and vesicle-bullous lesions associated with systemic symptoms. The patient was treated with prednisone 0.5 mg/kg/day with a dramatic response. The FUMHD is a severe variant of PLEVA and its diagnosis is clinical and histopathological. Many treatments such as methotrexate, corticosteroids and PUVA have been described. However, none of them has been settled.