Primary small bowel neoplasms as a complication of celiac disease

• Published in: Gastroenterología y hepatología Vol. 32; no. 9; p. 618
• Main Authors: Garrido, Antonio, Luque, Angel, Vázquez, Antonio, Hernández, José María, Alcántara, Federico, Márquez, José Luis
• Format: Journal Article
• Language: Spanish
• Published: Spain 01-11-2009
• Subjects: Adenocarcinoma - etiology; Aged; Celiac Disease - complications; Duodenal Neoplasms - etiology; Female; Humans; Ileal Neoplasms - etiology; Middle Aged
• ISSN: 0210-5705
• DOI: 10.1016/j.gastrohep.2009.05.003

Celiac disease is produced by gluten intake in genetically susceptible children and adults and is the most common severe food intolerance in western countries. Eliminating gluten from the diet is essential in these patients, since most of the complications that can occur are more frequent if there is lack of treatment adherence. The most serious complication in these patients is the development of neoplasms, the most frequent being enteropathy-associated T-cell lymphoma; however, an increase in the incidence of small bowel adenocarcinoma has also been described. We present two cases of small bowel carcinoma in patients with celiac disease, which were diagnosed at the onset of the disease.