Refractory angina treated by spinal cord stimulation. The results of a long-term follow-up

• Published in: Revista española de cardiologia Vol. 53; no. 3; pp. 321 - 326
• Main Authors: García-Moll, M, Serra, R, García-Moll, X
• Format: Journal Article
• Language: Spanish
• Published: Spain 01-03-2000
• Subjects: Aged; Angina Pectoris - therapy; Angina, Unstable - therapy; Chi-Square Distribution; Electric Stimulation Therapy - instrumentation; Electric Stimulation Therapy - methods; Electric Stimulation Therapy - statistics & numerical data; Female; Follow-Up Studies; Humans; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Spinal Cord; Statistics, Nonparametric; Time Factors
• ISSN: 0300-8932
• DOI: 10.1016/S0300-8932(00)75099-8

The quality of life in patients with refractory angina has been shown to improve dramatically with spinal cord stimulation because of its beneficial results. The aim of this study was to assess the long-term morbimortality of this technique of spinal cord stimulation in the long term.
41 patients with refractory angina and treated with spinal cord stimulation were included. Median follow-up was 31.0 [12.0-42.5] months, and total follow-up was 1,236 months.
Annual number of admissions per patient year were dramatically reduced after spinal cord stimulation (2.31 vs. 0.28). Patients that died during follow-up had a 3-fold increase rate of admissions than patients that survived (0.37 vs. 0.19). However, patients that died during follow-up also had a lower admission rate after spinal cord stimulation (2.03 vs. 0.37). Overall mortality was 9.7%/year; cardiac mortality was 7.7%/year. Both figures are not different from those of other groups of patients with similar anatomical characteristics of coronary artery disease severity without spinal cord stimulation. Complications of this treatment were minimal (we only observed an early post implantation infection and a battery extrusion, without any complications with electrodes). The outcome was similar in patients with subacute unstable refractory angina or stable angina.
Spinal cord stimulation can be considered a safe and effective alternative treatment of refractory angina. Long-term morbidity is low, and mortality is not higher than the expected in this group of patients.