Antihypoxic properties of GABA-containing vitamin derivatives

The antihypoxic properties of GABA-containing vitamin derivatives (pyridoxalphosphate-GABA, picamilone, pantogam, sodium homopantothenate) as compared with GABA were studied. All agents were found to increase mouse life expectancy under hypoxia in contrast to GABA.

Saved in:

Bibliographic Details
Published in:	Farmakologiia i toksikologiia Vol. 52; no. 1; p. 56
Main Authors:	Karaev, A L, Kovler, M A, Avakumov, V M, Kopelevich, V M, Bulanova, L N
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-01-1989
Subjects:	Animals Drug Evaluation, Preclinical gamma-Aminobutyric Acid - analogs & derivatives gamma-Aminobutyric Acid - therapeutic use Hypoxia - chemically induced Hypoxia - drug therapy Male Mice Nitroprusside Pantothenic Acid - analogs & derivatives Pantothenic Acid - therapeutic use Pyridoxal Phosphate - analogs & derivatives Pyridoxal Phosphate - therapeutic use Vitamins - therapeutic use
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	The antihypoxic properties of GABA-containing vitamin derivatives (pyridoxalphosphate-GABA, picamilone, pantogam, sodium homopantothenate) as compared with GABA were studied. All agents were found to increase mouse life expectancy under hypoxia in contrast to GABA.
ISSN:	0014-8318