Serum concentrations of pregnancy-associated alpha-2-glycoprotein in diabetic pregnancy complicated by nonfulminant and fulminant proliferative retinopathy

The pregnancy zone protein serum concentration in normal pregnancy reaches its peak at about the 24th week. High serum PZ concentrations are significantly more frequent among pregnant diabetic patients without proliferative retinopathy. In contrast, the mean values in mothers with diabetes mellitus...

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Bibliographic Details
Published in:	Zentralblatt für Gynäkologie Vol. 113; no. 19; p. 1042
Main Authors:	Briese, V, Straube, W, Glöckner, E
Format:	Journal Article
Language:	English
Published:	Germany 1991
Subjects:	Adolescent Adult Blood Glucose - chemistry Diabetic Retinopathy - blood Female Humans Immunodiffusion Predictive Value of Tests Pregnancy Pregnancy in Diabetics - blood Pregnancy Proteins - chemistry Prognosis Risk Factors
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Summary:	The pregnancy zone protein serum concentration in normal pregnancy reaches its peak at about the 24th week. High serum PZ concentrations are significantly more frequent among pregnant diabetic patients without proliferative retinopathy. In contrast, the mean values in mothers with diabetes mellitus complicated by proliferative retinopathy continue to decrease. A very low limit of 150 mg/l was achieved more frequently in diabetic pregnancy complicated by fulminant proliferative retinopathy. Measurement of serum PZ levels in diabetic pregnancy might help to predict the risk of progressive retinopathy.
ISSN:	0044-4197