Liver morphology in delta virus hepatitis

Biopsy material from two groups of patients with liver diseases is studied. 12 patients with a high titer of total anti-delta (D)-antibodies are included into the 1st group. In this group, among patients with total antibodies to D-infection D-antigen in the liver tissue is found in 6 cases with a pr...

Full description

Saved in:

Bibliographic Details
Published in:	Arkhiv patologii Vol. 51; no. 10; p. 18
Main Authors:	Loginov, A S, Aruin, L I, Shatalova, O L, Krenchyk, D, Ponomarenko, A M
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 1989
Subjects:	Adolescent Adult Aged Antigens, Viral - analysis Biopsy Chronic Disease Female Hepatitis Antibodies - analysis Hepatitis D - enzymology Hepatitis D - immunology Hepatitis D - pathology Hepatitis Delta Virus - immunology Histocytochemistry Humans Liver - enzymology Liver - immunology Liver - pathology Male Middle Aged Retrospective Studies
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Biopsy material from two groups of patients with liver diseases is studied. 12 patients with a high titer of total anti-delta (D)-antibodies are included into the 1st group. In this group, among patients with total antibodies to D-infection D-antigen in the liver tissue is found in 6 cases with a pronounced chronic aggressive hepatitis (CAH) and active liver cirrhosis (ALC). The 2nd group consisted of 30 patients with CAH and ALC and D-antigen was observed in 10 cases. Hepatocyte degeneration and pronounced lobular infiltration were the only distinctive feature of liver morphology in D-positive cases as compared to the D-negative ones. The presence of D-antigen always correlated with an active inflammatory process.
ISSN:	0004-1955