Somatic segregation and Fanconi anemia

A case of Fanconi anemia with terminal acute leukemia is reported. Clones with chromosome abnormalities were observed in bone marrow cells. The patterns of marker chromosome distribution in these clones suggests the occurrence of a somatic segregation mechanism.

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Bibliographic Details
Published in:	Clinical genetics Vol. 11; no. 6; p. 409
Main Authors:	Berger, R, Bussel, A, Schenmetzler, C
Format:	Journal Article
Language:	English
Published:	Denmark 01-06-1977
Subjects:	Acute Disease Adult Anemia, Aplastic - genetics Chromosome Aberrations Fanconi Anemia - genetics Female Humans Leukemia - genetics
Online Access:	Get more information
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Description
Summary:	A case of Fanconi anemia with terminal acute leukemia is reported. Clones with chromosome abnormalities were observed in bone marrow cells. The patterns of marker chromosome distribution in these clones suggests the occurrence of a somatic segregation mechanism.
ISSN:	0009-9163