Clinical diagnosis and treatment analysis of 21 cases of intrathyroid thymic carcinoma

• Published in: Zhong hua yi xue za zhi Vol. 104; no. 6; p. 440
• Main Authors: Feng, G C, Liu, Z, Li, H Q, Zuo, D H, Sun, H L, Qiao, L X, Yin, D T
• Format: Journal Article
• Language: Chinese
• Published: China 06-02-2024
• Subjects: Adult; Female; Humans; Lymph Node Excision; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Neoplasms, Glandular and Epithelial; Prognosis; Retrospective Studies; Thymoma - diagnosis; Thymoma - therapy; Thymus Neoplasms - diagnosis; Thymus Neoplasms - therapy
• ISSN: 0376-2491
• DOI: 10.3760/cma.j.cn112137-20231008-00676

To analyze the clinical efficacy of intrathyroid thymic carcinoma (ITTC).
This study retrospectively analyzed the clinical data of 21 patients with ITTC diagnosed and treated at the First Affiliated Hospital of Zhengzhou University from January 2018 to July 2023, including 9 males and 12 females, with a median age of 52 years (40-60 years old).
There is a correlation between the maximum diameter of the tumor (≥40 mm) and lymph node metastasis (
=0.044). Seventeen patients received surgical treatment, and 4 patients only received chemotherapy. During the follow-up period, a total of 4 patients experienced death or progression, with a 2-year mortality or progression free survival rate of 74.8%.
The prognosis of ITTC is good, and surgical treatment is the preferred treatment option, lymph node metastasis is significantly correlated with prognosis. The radiotherapy and chemotherapy of ITTC need to be determined based on the patient's condition.