Unicentric Castleman's disease: an uncommon cause of chronic cough

Castleman disease (CD) or angiofollicular lymph node hyperplasia is a rare lymphoproliferative disorder characterized by lymph node hyperplasia of uncertain etiology. CD is divided clinically into unicentric (localized to one region of the body) considered as a benign disease and multicentric with l...

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Bibliographic Details
Published in:	Tunisie Medicale Vol. 96; no. 2; p. 148
Main Authors:	Bacha, Saoussen, Zribi, Hazem, Habibech, Sonia, Attia, Monia, Ayadi, Aida, Mezni, Faouzi, Chabbou, Abdellatif
Format:	Journal Article
Language:	English
Published:	Tunisia 01-02-2018
Subjects:	Castleman Disease - complications Castleman Disease - diagnosis Chronic Disease Cough - diagnosis Cough - etiology Diagnosis, Differential Female Humans Middle Aged
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Summary:	Castleman disease (CD) or angiofollicular lymph node hyperplasia is a rare lymphoproliferative disorder characterized by lymph node hyperplasia of uncertain etiology. CD is divided clinically into unicentric (localized to one region of the body) considered as a benign disease and multicentric with less favourable prognosis. We describe a case of intrathoracic unicentric CD revealed by a chronic non-productive cough in a 50-year-old non-smoker female. Chest computed tomography revealed a bulky right hilar mass with intense homogenous contrast enhancement. The patient underwent a right upper lobectomy and mediastinal lymphadenectomy. Histopathology was consistent with hyaline-vascular (HV) type CD. The patient remained asymptomatic throughout the subsequent 6-months of follow-up.
ISSN:	0041-4131