Comparison of therapeutic effects between acupoint-injection and intramuscular-injection of Bacillus Calmette-Guerin polysaccharide nucleic acid for bronchial asthma

• Published in: Zhēncì yánjiū Vol. 40; no. 1; p. 65
• Main Authors: Zou, Xian, Zhu, Jing, Kang, Xin-zhong, Hu, Wei-yong, Wang, Kang, Peng, Zhong-juan, Fu, Ying, Zi, Xiao-fei
• Format: Journal Article
• Language: Chinese
• Published: China 01-02-2015
• Subjects: Acupuncture Points; Adolescent; Adult; Asthma - blood; Asthma - drug therapy; Asthma - physiopathology; Bacillus - chemistry; Female; Humans; Immunoglobulin A - blood; Immunoglobulin E - blood; Immunoglobulin G - blood; Injections, Intramuscular; Male; Middle Aged; Nucleic Acids - administration & dosage; Polysaccharides - administration & dosage; Respiratory Function Tests; Treatment Outcome; Young Adult
• ISSN: 1000-0607

To observe the curative effect of acupoint-injection and intramuscular-injection of Bacillus Calmette-Guerin (BCG) Polysaccharide Nucleic Acid for bronchial asthma.
Sixty patients with bronchial asthma were equally randomized into acupoint-injection group and intramuscular-injection group. For patients of the acupoint-injection group, 2 mL of BCG was injected into bilateral Feishu (BL 13, 1 mL for one side) once per day in the first 15 days, and once every other day in the rest 2.5 months except weekends. Intramuscular-injection was conducted at the lateral sites of the left or right buttock, 2 mL/time for each site, and the injection frequency was the same to that of the acupoint-injection. The therapeutic effect was assessed according to the standards of Guide Principles for Clinical Research of New Chinese Herbal Drugs (2002) and Asthma Group of Breathing Diseases of China Medical Association (2008). Changes of FEV 1 (forced expiratory volume in the first second)/FVC (forced vital capacity) and PEF% (peak