Exercise-related risk at anaerobic threshold in patients with chronic obstructive pulmonary disease

• Published in: Zhonghua jiehe he huxi zazhi Vol. 39; no. 2; p. 110
• Main Authors: Xu, Q F, Yuan, W, Zhao, X J, Li, B, Wang, H Y
• Format: Journal Article
• Language: Chinese
• Published: China 01-02-2016
• Subjects: Aged; Anaerobic Threshold; Carbon Dioxide - analysis; Electrocardiography; Exercise Test; Female; Humans; Male; Middle Aged; Oximetry; Oxygen - analysis; Pulmonary Disease, Chronic Obstructive - physiopathology
• ISSN: 1001-0939
• DOI: 10.3760/cma.j.issn.1001-0939.2016.02.008

To investigate the exercise-related risk at anaerobic threshold(AT) in patients with chronic obstructive pulmonary disease(COPD).
Sixty two patients [men 56, women 6, aged (66±8) yr] with stable COPD in Beijing Friendship Hospital during 2013-2014, participated in this study. Incremental symptom-limited cardiopulmonary exercise test was performed on cycle ergometer. The AT was determined using the V-Slope technique and ventilatory equivalents for carbon dioxide and oxygen. Symptoms, 10-lead electrocardiogram, oxygen saturation by pulse oximetry(SpO(2)) were monitored during exercise.
The AT, detectable in 53 patients, occurred at (68±10)% of peak oxygen uptake(peak VO(2)). The SpO(2) was in the safe range (94±2) % and the respiratory reserve was relatively high at AT (i.e. 48%).
High-intensity exercise training can be performed in patients with moderate-to- severe COPD without resting oxygen desaturation.