Biological function of Nogo-B

Nogo-B is a major family member of the reticulon protein family 4. It is widely expressed in the central nervous system and peripheral tissues, and is mainly located in endoplasmic reticulum and cell membrane. Previous studies have revealed that Nogo-B plays a key role in vascular injury, tissue rep...

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Bibliographic Details
Published in:	Sheng li hsüeh pao Vol. 65; no. 4; p. 445
Main Authors:	Xu, Wu-Jian, Shen, Guo-Qing, Li, Qiang
Format:	Journal Article
Language:	Chinese
Published:	China 25-08-2013
Subjects:	Animals Apoptosis Cell Membrane - physiology Endoplasmic Reticulum - physiology Humans Inflammation Myelin Proteins - physiology Nogo Proteins
Online Access:	Get more information
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Summary:	Nogo-B is a major family member of the reticulon protein family 4. It is widely expressed in the central nervous system and peripheral tissues, and is mainly located in endoplasmic reticulum and cell membrane. Previous studies have revealed that Nogo-B plays a key role in vascular injury, tissue repair and inflammation process. It also may be critical for apoptosis of tumor cells and central diseases. Further investigation of the molecular characteristics and biological function of Nogo-B might be of great help to understand its role in diverse diseases.
ISSN:	0371-0874