PHOTODYNAMIC THERAPY FOR INTRADERMAL METASTASES OF BREAST CANCER USING THE MATRIX LIGHT-EMITTING DIODES APPARATUS LATUS

There are presented results of photodynamic therapy (PDT) for patients with chemo- and radioresistant intradermal metastases of breast cancer using the matrix light-emitting diodes apparatus. To all patients prior to irradiation there was performed fluorescence diagnostics to assess the accumulation...

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Bibliographic Details
Published in:	Voprosy onkologij Vol. 61; no. 3; p. 430
Main Authors:	Gelfond, M L, Ivanov, V G, Semiglazov, V F, Vorotnikov, V V, Belousova, T A, Zhiltsova, E K, Ivanova, O A, Ermilova, E V, Fedosov, S I
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 2015
Subjects:	Breast Neoplasms - pathology Female Humans Middle Aged Photochemotherapy - instrumentation Photochemotherapy - methods Photosensitizing Agents - therapeutic use Skin Neoplasms - drug therapy Skin Neoplasms - secondary Treatment Outcome
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Summary:	There are presented results of photodynamic therapy (PDT) for patients with chemo- and radioresistant intradermal metastases of breast cancer using the matrix light-emitting diodes apparatus. To all patients prior to irradiation there was performed fluorescence diagnostics to assess the accumulation of the photosensitizer of chlorine series and photobleaching during PDT. The size of the irradiation area was 400 sm, the total dose of irradiation was 250J/cm2. PDT was accompanied by mild pain, which was stopped by administration of non-narcotic analgesics. Complete regression of intradermal lesions was registered in 2 of 4 cases, partial response was observed in 1 patient and the progression of the process in 1 case.
ISSN:	0507-3758