The analysis of level of total immunoglobulin E (IgE) in blood serum of patients with various types of disorders of carbohydrate metabolism and blood groups 0 (I), A (II) and B (III).

• Published in: Klinicheskaia laboratornaia diagnostika Vol. 62; no. 8; p. 476
• Main Authors: Telesmanich, N R, Konoval Chik, M A, Mikashinovich, Z I
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 2017
• Subjects: Blood Group Antigens; Carbohydrate Metabolism; Carbohydrate Metabolism, Inborn Errors - blood; Diabetes Mellitus - blood; Humans; Immunoglobulin E - blood; blood groups (AB0); diabetes mellitus; immunoglobulin E, IgE; total IgE; disorders of carbohydrate metabolism
• ISSN: 0869-2084
• DOI: 10.18821/0869-2084-2017-62-8-476-481

The analysis was applied to indices of IgE-mediated immunological reaction (total IgE) in patients with disorders of carbohydrate metabolism and diabetes and different blood groups (AB0) (n=93). The coefficient of pair correlation established a direct relationship between blood group 0 (I) and risk of development of diabetes type II (r=0.8) and higher risk of development of diabetes type I in patients with blood group A (II) (r=1). The average values of indices of total IgE in patients with blood groups 0 (I) and A (II) were compared and significantly differed the level of total IgE of blood group B (III). In case of expressed disorder of carbohydrate metabolism patients with blood groups 0 (I) and A (II) had indices of total IgE 43,61±15,12 и 86,2±42,61 kIU/l correspondingly that in average is four times lower than indices of patients with blood group B (III) who in case of diabetes type II had total IgE increased twice relatively to upper limit of standard amounting to 209,65±52,5 кIU/l.