A Case Report of Recurrent Bleeding and Massive Malodorous Effusion Due to Skin Invasion of Advanced Breast Cancer Successfully Treated with Mohs' Paste

We report a case involving a 65-year-old woman with skin invasion and destruction by left large breast cancer(T4cN0M0, Stage ⅢB). She had severe anemia with recurrent bleeding on the cancer surface and needed blood transfusion, and massive malodorous effusion from the skin lesion resulted in hypoalb...

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Bibliographic Details
Published in:	Gan to kagaku ryoho Vol. 45; no. 13; p. 1997
Main Authors:	Satoh, Eigo, Osanai, Takayuki, Tomi, Yoshiaki, Nakamura, Masahiro, Yonekura, Koji, Murakata, Ayano, Motoyama, Kazuo, Tanami, Hideo, Sugano, Norihide, Sakoma, Takaaki
Format:	Journal Article
Language:	Japanese
Published:	Japan 01-12-2018
Subjects:	Aged Breast Neoplasms - complications Breast Neoplasms - drug therapy Chlorides - therapeutic use Female Hemorrhage - etiology Humans Skin Neoplasms - drug therapy Skin Neoplasms - pathology Zinc Compounds - therapeutic use
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Summary:	We report a case involving a 65-year-old woman with skin invasion and destruction by left large breast cancer(T4cN0M0, Stage ⅢB). She had severe anemia with recurrent bleeding on the cancer surface and needed blood transfusion, and massive malodorous effusion from the skin lesion resulted in hypoalbuminemia and recurrent bacteremia. Metronidazole gel treatment for malodorous effusion and postmenopausal hormonal therapy were administered at first. After using Mohs' paste 4 times with 1- or 2-week intervals, the bleeding and effusion stopped, and the primary cancer tumor almost disappeared. Bacteremia also improved with antibiotics, and amelioration of distress was observed. Following this, systemic chemotherapy was performed. Mohs' paste was a very useful method for symptom management of malignant skin lesions with bleeding and massive effusion.
ISSN:	0385-0684