Platelet dysfunction in acute leukemias and myelodysplastic syndromes

The hemorrhagic and thrombotic diathesis represents a frequent complication in myelodysplastic syndromes (MDS) and in acute leukemias. They are correlated with the number of the platelets, but also with their qualitative disorders, such as membrane glycoprotein changes. The latter are revealed by ma...

Full description

Saved in:

Bibliographic Details
Published in:	Revue roumaine de médecine interne (1990) Vol. 49; no. 1; p. 93
Main Authors:	Vlădăreanu, Ana Maria, Vasilache, Veronica, Bumbea, H, Onisâi, Minodora
Format:	Journal Article
Language:	English
Published:	Germany 2011
Subjects:	Acute Disease Blood Platelet Disorders - blood Blood Platelet Disorders - etiology Blood Platelet Disorders - pathology Blood Platelets - metabolism Blood Platelets - pathology Flow Cytometry Humans Leukemia - blood Leukemia - complications Myelodysplastic Syndromes - blood Myelodysplastic Syndromes - complications Platelet Aggregation Platelet Count Platelet Function Tests Platelet Membrane Glycoproteins - classification Platelet Membrane Glycoproteins - metabolism
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	The hemorrhagic and thrombotic diathesis represents a frequent complication in myelodysplastic syndromes (MDS) and in acute leukemias. They are correlated with the number of the platelets, but also with their qualitative disorders, such as membrane glycoprotein changes. The latter are revealed by many platelet studies including flow-cytometry and comprise modified activation, secretion and aggregation patterns.
ISSN:	1220-4749